drugset / Trial / NCT05575297
A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin and Febuxostat on the Pharmacokinetics of Methotrexate in Healthy Subjects
RandomizedCrossoverOpen-labelBasic science
Summary
To investigate the effect of rifampicin and febuxostat on pharmacokinetics of methotrexate in healthy volunteers
Timeline
- Start
- 2021-12-20
- Primary completion
- 2022-05-03
- Completion
- 2022-05-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Febuxostat | Small molecule | — | — |
| Subject | Methotrexate | Small molecule | — | Oral |
| Subject | Rifampicin | Small molecule | — | — |
Indications
No indication recorded.