drugset / Trial / NCT05576272

A Phase II/III Trial to Evaluate the Efficacy and Safety of QL1706 in Patients With Nasopharyngeal Carcinoma

NCT05576272

Phase 2/3 Unknown 460 enrolled Qilu Pharmaceutical Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a randomized, open, multicenter phase II/III trial to compare the efficacy and safety of QL1706 and carrilizumab combined with gemcitabine and cisplatin in first-line treatment of recurrent or metastatic nasopharyngeal carcinoma.

Timeline

Start
2022-05-19
Primary completion
2024-12-30
Completion
2024-12-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Camrelizumab Monoclonal antibody 200 mg Intravenous
Subject QL1706 Monoclonal antibody 5 mg/kg Intravenous
Background Cisplatin Other / unclassified 80 mg/m2 Intravenous
Background Gemcitabine Small molecule 1000 mg/m2 Intravenous