drugset / Trial / NCT05577585
Ketamine in OCD: Efficacy and Effects on Stress and Cognition
RandomizedCrossoverTriple-blindTreatment
Summary
The main goal of this trial is to demonstrate therapeutic efficacy of low dose ketamine in patients with OCD. We expect that ketamine will alleviate symptoms in the hours following application, but also - if effective - that the anti-OCD effects might last for several days after a single infusion.
Timeline
- Start
- 2022-10-01
- Primary completion
- 2026-06
- Completion
- 2026-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ketamine | Small molecule | 0.5 mg/kg | — |
| Comparator | Midazolam | Small molecule | 0.045 mg/kg | — |