drugset / Trial / NCT05578430

AK104 Combining With TACE for Resectable Hepatocellular Carcinoma (MORNING)

NCT05578430 ↗

Phase 2 Unknown 54 enrolled Sun Yat-sen University
NaSingle-groupOpen-labelTreatment

Summary

This is a Phase 2, open-label, single-arm study of neoadjuvant immune-checkpoint blockade therapy (AK104) combining with TACE for resectable hepatocellular carcinoma. The purpose is to investigate the efficacy and safety of this therapeutic regimen to reduce the risk of postoperative recurrence in resectable HCC patients with a high risk of recurrence.

Timeline

Start
2023-01-01
Primary completion
2025-01-01
Completion
2025-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cadonilimab Monoclonal antibody 10 mg/kg Intravenous