drugset / Trial / NCT05580601

Cytokine-Induced Memory-Like Natural Killer Cells (CIML-NK) for Relapsed & Refractory Acute Myeloid Leukemia (AML)

NCT05580601

Phase 1/2 Recruiting 20 enrolled Children's Hospital Medical Center, Cincinnati
NaSingle-groupOpen-labelTreatment

Summary

The objective of this study is to demonstrate that cytokine-induced memory-like natural killer cells can be generated from donor cells and infused safely into patients with relapsed or refractory acute myeloid leukemia (AML). A secondary objective is to assess efficacy of the CIML-NK cells in treating AML.

Timeline

Start
2023-05-05
Primary completion
2027-01
Completion
2027-07

Drugs

EvaluationDrugModalityDoseRoute
Subject CIML-NK Cells Cell therapy