drugset / Trial / NCT05582161

Efficacy Biomarkers of DAOIB for Dementia

NCT05582161 ↗

Phase 2 Recruiting 123 enrolled Chang Gung Memorial Hospital
NaSingle-groupOpen-labelTreatment

Summary

This open-label clinical trial will enroll patients with aMCI or mild AD, and they will be treated with DAOIB for 24 weeks. We will assess the patients before entering the study, 8 weeks, 16 weeks, and end point (24 weeks) of the study, and measure blood NMDA and oxidative stress - related biomarkers every 8 weeks. We hypothesize that NMDA and oxidative stress - related biomarkers can predict the efficacy of DAOIB for patients with aMCI or mild AD.

Timeline

Start
2022-10-03
Primary completion
2026-09
Completion
2026-09

Drugs

EvaluationDrugModalityDoseRoute
Subject DAOIB Unknown — —

Indications