drugset / Trial / NCT05583643

Clinical & Biochemical Effect of Atorvastatin in Nano Particles Gel in Periodontitis Treatment

NCT05583643

Phase 1 Completed 24 enrolled Misr University for Science and Technology
RandomizedParallel-groupOpen-labelTreatment

Summary

Periodontitis is a destructive chronic inflammatory disease characterized by periodontium damage and pocket formation between the tooth and the gingival margin resulting in ultimate tooth loss. Various topical anti-inflammatory drugs were used to treat inflammation in periodontitis. Introducing atorvastatin as a novel remedy for periodontitis treatment necessitates developing a syringeable modified delivery system capable of targeting inflammation within the periodontal pockets.

Timeline

Start
2021-12-07
Primary completion
2022-04-15
Completion
2022-06-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Atorvastatin Small molecule Other

Indications