drugset / Trial / NCT05583643
Clinical & Biochemical Effect of Atorvastatin in Nano Particles Gel in Periodontitis Treatment
RandomizedParallel-groupOpen-labelTreatment
Summary
Periodontitis is a destructive chronic inflammatory disease characterized by periodontium damage and pocket formation between the tooth and the gingival margin resulting in ultimate tooth loss. Various topical anti-inflammatory drugs were used to treat inflammation in periodontitis. Introducing atorvastatin as a novel remedy for periodontitis treatment necessitates developing a syringeable modified delivery system capable of targeting inflammation within the periodontal pockets.
Timeline
- Start
- 2021-12-07
- Primary completion
- 2022-04-15
- Completion
- 2022-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atorvastatin | Small molecule | — | Other |