drugset

drugset / Trial / NCT05586750

Statins in Reducing Events in the Elderly Mind (STAREE-Mind) Imaging Substudy

NCT05586750 ↗

Phase 4 Active not recruiting 341 enrolled Monash University National Health and Medical Research Council, Australia · collab

RandomizedParallel-groupQuadruple-blindPrevention

Summary

The STAREE-Mind imaging sub-study will examine the effect of statin treatment over a 4-year period, compared with placebo, on markers of brain health.

Timeline

Start: 2019-09-19
Primary completion: 2026-09
Completion: 2026-09

Publications

Harding IH, Ryan J, Heritier S, Spark S, Flanagan Z, McIntyre R, Anderson CS, Naismith SL, Chong TT, O'Sullivan M, Egan G, Law M, Zoungas S. STAREE-Mind Imaging Study: a randomised placebo-controlled trial of atorvastatin for prevention of cerebrovascular decline and neurodegeneration in older individuals. BMJ Neurol Open. 2023 Oct 31;5(2):e000541. doi: 10.1136/bmjno-2023-000541. eCollection 2023.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Atorvastatin	Small molecule	40 mg	Oral

Indications