drugset / Trial / NCT05588531
Study on Tolerance, Pharmacokinetics and Drug Interaction of YK-1169 in Healthy Volunteers
RandomizedFactorialTriple-blindBasic science
Summary
To evaluate the safety and tolerability of multiple doses of YK-1169 in healthy subjects, the pharmacokinetic characteristics of multiple doses in healthy subjects, and the drug interaction between cefepime and avibactam.
Timeline
- Start
- 2021-12-20
- Primary completion
- 2022-04-02
- Completion
- 2022-04-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cefepime | Small molecule | 2 g | Intravenous |
| Comparator | YK-1169 | Unknown | 0.5 g | Intravenous |
| Comparator | YK-1169 | Unknown | 1.25 g | Intravenous |
| Comparator | YK-1169 | Unknown | 2.5 g | Intravenous |
| Comparator | YK-1169 | Unknown | 3.75 g | Intravenous |
| Comparator | YK-1169 | Unknown | 5 g | Intravenous |
| Comparator | avibactam | Small molecule | 0.5 g | Intravenous |
Indications
No indication recorded.