drugset / Trial / NCT05590377

A Study of Modakafusp Alfa Together With Daratumumab Adults With Relapsed or Refractory Multiple Myeloma

NCT05590377

Phase 1/2 Terminated 15 enrolled Teva Branded Pharmaceutical Products R&D, Inc.
RandomizedSequentialOpen-labelTreatment

Summary

The main aim of this study is to determine safety and tolerability of modakafusp alfa given together with daratumumab to find out the best treatment dose. Another aim of this study is to learn more about the characteristics of modakafusp alfa.

Timeline

Start
2023-01-23
Primary completion
2024-05-22
Completion
2024-05-22

Drugs

EvaluationDrugModalityDoseRoute
Subject Modakafusp alfa Protein / enzyme biologic 80 mg Intravenous
Subject Modakafusp alfa Protein / enzyme biologic 120 mg Intravenous
Subject Modakafusp alfa Protein / enzyme biologic 240 mg Intravenous
Background Daratumumab Monoclonal antibody 1800 mg Subcutaneous

Indications