drugset / Trial / NCT05596669

Analgesic Effect of Ketamine Vs Ketamine Magnesium Infusion and Their Effect on Postoperative Morphine Consumption

NCT05596669

Phase 1 Completed 100 enrolled Egymedicalpedia
RandomizedParallel-groupSingle-blindTreatment

Summary

Ketamine and magnesium-ketamine are two analgesics that are being studied for use as adjuvants. They were shown to have anaesthetic and analgesic properties, and as a consequence of this finding, it has been postulated that they may have a role in minimising the requirement for analgesic drugs during the postoperative period. The major objective of the research was to examine the pain-relieving effects of ketamine vs ketamine magnesium infusion, as well as their influence on postoperative morphine consumption following nephrectomy; the secondary goal is to assess hemodynamic effects and pain severity.

Timeline

Start
2021-09-01
Primary completion
2022-05-01
Completion
2022-05-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ketamine Small molecule 0.15 mg/kg Other

Indications