drugset / Trial / NCT05597241
Multiple Ascending Dose and Electroencephalography Trial of GATE-202 in Healthy Volunteers
RandomizedSequentialQuadruple-blindTreatment
Summary
To evaluate the safety, tolerability, pharmacokinetics and EEG pharmacodynamics of single and multiple ascending doses of apimostinel in normal human volunteers
Timeline
- Start
- 2022-10-15
- Primary completion
- 2023-04-04
- Completion
- 2023-04-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Apimostinel | Protein / enzyme biologic | 1 mg | Intravenous |
| Subject | Apimostinel | Protein / enzyme biologic | 5 mg | Intravenous |
| Subject | Apimostinel | Protein / enzyme biologic | 10 mg | Intravenous |
| Subject | Apimostinel | Protein / enzyme biologic | 25 mg | Intravenous |