Chemotherapy and Sequential Immunotherapy for Locally Advanced Urothelial Cancer

Summary

Patients with locally advanced or clinically node positive urothelial carcinoma treated with chemotherapy, will receive 3 cycles of avelumab, followed by radical surgery.

Timeline

Start

2022-12-01

Primary completion

2025-04

Completion

2026-12

Publications

• Rutten VC, Salhi Y, Robbrecht GJ, de Wit R, van Leenders GJLH, Zuiverloon TCM, Boormans JL. The CHASIT study: sequential chemo-immunotherapy in patients with locally advanced urothelial cancer - a non-randomized phase II clinical trial. BMC Cancer. 2023 Jun 13;23(1):539. doi: 10.1186/s12885-023-10963-7.

Drugs

Indications