drugset / Trial / NCT05606965
A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in Healthy Adults
RandomizedParallel-groupOpen-labelPrevention
Summary
The main purpose of the study is to evaluate the safety, reactogenicity, and the humoral immunogenicity of mRNA-1010 and comparator influenza vaccines against homologous influenza A and B strains at Day 29.
Timeline
- Start
- 2022-11-02
- Primary completion
- 2025-11-13
- Completion
- 2025-11-13
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Adjuvanted Quadrivalent Influenza Vaccine | Vaccine | — | Intramuscular |
| Comparator | Egg-based Quadrivalent Influenza Vaccine | Vaccine | — | Intramuscular |
| Comparator | Inactivated Influenza Vaccine | Vaccine | — | Intramuscular |
| Subject | mRNA-1010 | Messenger RNA (mRNA) | — | Intramuscular |
| Subject | mRNA-1045 | Unknown | — | Intramuscular |
| Subject | mRNA-1345 | Messenger RNA (mRNA) | — | — |