drugset / Trial / NCT05608876

A Clinical Study to Investigate the Efficacy of Tigilanol Tiglate Directly in Head and Neck Cancer

NCT05608876 ↗

Phase 2 Active not recruiting 15 enrolled QBiotics Group Limited
NaSingle-groupOpen-labelTreatment

Summary

A Phase II, open label, single arm study to assess the efficacy of intratumoural tigilanol tiglate in various head and neck solid malignancies.

Timeline

Start
2022-11-03
Primary completion
2025-07-31
Completion
2026-08

Outcome

Met primary endpoint

release “64% of response-evaluable patients (9 of 14) achieved complete or partial ablation of a treated tumour or tumour segment, meeting the primary efficacy endpoint” qbiotics.com ↗

Drugs

EvaluationDrugModalityDoseRoute
Subject Tigilanol Tiglate Small molecule 3.6 mg/m2 Other

Indications