Electroporation and Immunotherapy in Metastatic Colorectal Cancer

Summary

The trial is designed as an investigator initiated prospective phase 2 study in patients with metastatic pMMR colorectal cancer (CRC) to determine the safety and efficacy of calcium electroporation (CaEP) performed concurrently with irreversible electroporation (IRE) followed by a PD-1 inhibitor (pembrolizumab).

Timeline

Start

2023-01-26

Primary completion

2024-04-08

Completion

2024-05-02

Outcome

Outcome not reported

Stopped: “The study was terminated on the basis on an evaluation of the efficacy and safety of the 4 included and treated patients.”

Drugs

Indications