drugset / Trial / NCT05610826

Preoperative PRRT Versus Surgical Cytoreduction in Metastatic Pancreatic Neuroendocrine Tumors to the Liver

NCT05610826

Phase 1/2 Withdrawn University of Chicago
RandomizedParallel-groupOpen-labelTreatment

Summary

Doctors and researchers leading this study hope to learn more about peptide receptor radionuclide therapy (PRRT) in combination with cytoreduction (surgically removing tumors). They hope to learn if combining PRRT in combination with cytoreduction would be more effective than cytoreduction alone. PRRT itself is approved by the U.S. Food and Drug Administration (FDA) for people with PanNETs however the combination with cytoreduction is considered experimental. Your participation in this research will last about 2 years. The purpose of this research is to gather information on the safety and effectiveness of PRRT.

Timeline

Start
2023-03-07
Primary completion
2024-09-11
Completion
2024-09-11

Drugs

EvaluationDrugModalityDoseRoute
Subject 177Lu-DOTATATE Peptide Intravenous