drugset / Trial / NCT05615363
A Dose-ranging Trial of OPC-131461 in Cardiac Edema (Congestive Heart Failure [CHF])
RandomizedParallel-groupQuadruple-blindTreatment
Summary
To investigate the dose response in respect of weight decrease following repeated oral administration of OPC-131461 at 1, 2, 5, and 10 mg or placebo in patients with CHF with volume overload despite having received diuretics other than vasopressin antagonists
Timeline
- Start
- 2023-01-10
- Primary completion
- 2024-10-21
- Completion
- 2024-10-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | OPC-131461 | Unknown | 1 mg | Oral |
| Subject | OPC-131461 | Unknown | 2 mg | Oral |
| Subject | OPC-131461 | Unknown | 5 mg | Oral |
| Subject | OPC-131461 | Unknown | 10 mg | Oral |