drugset / Trial / NCT05615363

A Dose-ranging Trial of OPC-131461 in Cardiac Edema (Congestive Heart Failure [CHF])

NCT05615363 ↗

Phase 2 Completed 157 enrolled Otsuka Pharmaceutical Co., Ltd.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

To investigate the dose response in respect of weight decrease following repeated oral administration of OPC-131461 at 1, 2, 5, and 10 mg or placebo in patients with CHF with volume overload despite having received diuretics other than vasopressin antagonists

Timeline

Start
2023-01-10
Primary completion
2024-10-21
Completion
2024-10-21

Drugs

EvaluationDrugModalityDoseRoute
Subject OPC-131461 Unknown 1 mg Oral
Subject OPC-131461 Unknown 2 mg Oral
Subject OPC-131461 Unknown 5 mg Oral
Subject OPC-131461 Unknown 10 mg Oral