Treatment of Advanced Malignant Solid Tumors With Claudin18.2CAR-T

Summary

The efficacy of advanced pancreatic cancer and gastric cancer needs to be further improved. Claudin is a kind of integrin membrane protein in the tight junction between epithelium and endothelium, which is highly expressed in gastric cancer and pancreatic cancer. Preclinical studies suggest that Claudin18.2CAR-T can effectively improve the remission rate of patients with advanced solid tumors.

Timeline

Start

2022-10-01

Primary completion

2025-10-31

Completion

2028-10-31

Drugs

Indications