drugset / Trial / NCT05624229
Efficacy of Proton Pump Inhibitors in Cirrhotic Patients With Acute Variceal Bleeding
RandomizedParallel-groupTriple-blindTreatment
Summary
Acute Variceal Bleeding (AVB) in patients with liver cirrhosis is a common clinical critical disease. There is little evidence for the effect of proton pump inhibitor (PPI) use in patients with AVB, and there is no study on the efficacy of PPI combined with standard therapy in patients with AVB.
Timeline
- Start
- 2023-10-01
- Primary completion
- 2025-12-31
- Completion
- 2028-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Esomeprazole | Small molecule | — | — |
| Subject | Ilaprazole | Small molecule | — | — |
| Subject | Lansoprazole | Other / unclassified | — | — |
| Subject | Omeprazole | Other / unclassified | — | — |
| Subject | Pantoprazole | Other / unclassified | — | — |
| Subject | Rabeprazole | Small molecule | — | — |