drugset / Trial / NCT05629559

4D-310 in Adults With Fabry Disease and Cardiac Involvement

NCT05629559 ↗

Phase 1/2 Recruiting 18 enrolled 4D Molecular Therapeutics
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a prospective multicenter, open-label, dose-escalation trial to assess the safety, tolerability, and pharmacodynamics of 4D-310 following a single IV administration. The study population is comprised of adult males and females with Fabry Disease and cardiac involvement

Timeline

Start
2022-10-16
Primary completion
2026-06
Completion
2030-06

Drugs

EvaluationDrugModalityDoseRoute
Subject DUVALGAGENE OTIPARVOVEC Gene therapy (AAV / viral vector) — Intravenous

Indications