drugset / Trial / NCT05630534
Minocycline Accelerates Intracerebral Hemorrhage Absorption
Phase 1
Unknown
90 enrolled
Second Affiliated Hospital, School of Medicine, Zhejiang University
The Fourth Affiliated Hospital of Zhejiang University School of Medicine · collabThe Second Affiliated Hospital of Jiaxing University · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
Minocycline has been found to reduce cerebral edema secondary to cerebral hemorrhage, promote hematoma absorption, and shorten hematoma absorption time; clinical studies have been conducted to confirm the safety in the treatment, but no significant hematoma absorption effect was seen with short duration of drug use. Therefore, the investigators propose to conduct a multicenter randomized controlled clinical trial to determine its accelerating effect on hematoma absorption.
Timeline
- Start
- 2023-01-01
- Primary completion
- 2024-12-31
- Completion
- 2024-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Minocycline | Small molecule | 100 mg | Oral |