drugset / Trial / NCT05631730
Effect and Safety of Flecainide and Metoprolol Versus Metoprolol Alone to Suppress Ventricular Arrhythmias in Arrhythmic Mitral Valve Prolapse
Phase 3
Recruiting
50 enrolled
Oslo University Hospital
The Research Council of Norway · collabUniversity of Oslo · collab
RandomizedCrossoverSingle-blindTreatment
Summary
FLECAPRO is a randomized controlled crossover trial assessing the effect and safety of adding flecainide to standard beta-blocker therapy to reduce the burden of ventricular arrhythmias in patients with arrhythmic mitral valve prolapse. The primary endpoint of will be assessed using an implantable loop recorder with blinded endpoint adjudication.
Timeline
- Start
- 2023-01-04
- Primary completion
- 2026-06
- Completion
- 2026-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metoprolol | Other / unclassified | — | — |
| Subject | flecainide | Small molecule | 100 mg | — |