drugset / Trial / NCT05632380
ASCT in Combination With C-CAR088 for Treating Patients With Ultra High-risk Multiple Myeloma (MM)
Phase 1/2
Recruiting
20 enrolled
Institute of Hematology & Blood Diseases Hospital, China
Shanghai AbelZeta Ltd. · collab
NaSingle-groupOpen-labelTreatment
Summary
This is a phase I/II, single-arm, open-lable study of autologous stem cell transplantation in combination with C-CAR088, an autologous BCMA CAR-T cell product, for patients with ulta high-risk multiple myeloma, defined as failed or unsatisfied responses to front line VRD-based treatment with or without the presence of multiple high-risk cytogenetic features.
Timeline
- Start
- 2022-07-14
- Primary completion
- 2025-10-30
- Completion
- 2026-04-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | C-CAR088 | Cell therapy | — | — |