drugset / Trial / NCT05633758

Metolazone As Early Add On Therapy For Acute Decompensated Heart Failure

NCT05633758

Phase 2 Withdrawn Scripps Health
RandomizedParallel-groupTriple-blindTreatment

Summary

The primary objective of the study is to determine efficacy of metolazone as synergistic therapy with Lasix in patients with acute decompensated heart failure. This will be a multicenter double blinded randomized placebo- controlled pilot study of the addition of 5 mg of metolazone per day for 2 days compared to placebo in patients admitted with acute decompensated heart failure.

Timeline

Start
2014-03
Primary completion
2016-03
Completion
2016-03

Drugs

EvaluationDrugModalityDoseRoute
Comparator Metolazone Small molecule 5 mg

Indications