drugset / Trial / NCT05633758
Metolazone As Early Add On Therapy For Acute Decompensated Heart Failure
RandomizedParallel-groupTriple-blindTreatment
Summary
The primary objective of the study is to determine efficacy of metolazone as synergistic therapy with Lasix in patients with acute decompensated heart failure. This will be a multicenter double blinded randomized placebo- controlled pilot study of the addition of 5 mg of metolazone per day for 2 days compared to placebo in patients admitted with acute decompensated heart failure.
Timeline
- Start
- 2014-03
- Primary completion
- 2016-03
- Completion
- 2016-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Metolazone | Small molecule | 5 mg | — |