drugset / Trial / NCT05634382
Endovascular Thrombectomy With and Without Intravenous Thrombolysis in Extended Time Window
RandomizedParallel-groupDouble-blindTreatment
Summary
The primary hypothesis being tested in this trial is that ischemic stroke patients in large vessel occlusion of anterior circulation at 4.5 - 9 hours post onset of stroke will have improved clinical outcomes when given endovascular thrombectomy with intravenous thrombolysis compared with that of given direct endovascular thrombectomy alone.
Timeline
- Start
- 2022-12-03
- Primary completion
- 2024-11-28
- Completion
- 2025-02-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Alteplase | Protein / enzyme biologic | — | Intravenous |
| Subject | Tenecteplase | Protein / enzyme biologic | — | Intravenous |