drugset / Trial / NCT05634876
UB-312 in Patients With Synucleinopathies
RandomizedParallel-groupSingle-blindTreatment
Summary
This is a Phase 1b study to determine the safety, tolerability, and immunogenicity of UB-312 in participants with multiple system atrophy (MSA), and in participants with Parkinson's disease (PD). UB-312 is a UBITh®-enhanced synthetic peptide-based vaccine and may provide an active immunotherapy option for treating synucleinopathies including the most prevalent form, PD; and the most rapidly progressive form, MSA.
Timeline
- Start
- 2023-05-31
- Primary completion
- 2025-02-11
- Completion
- 2025-02-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | UB-312 | Vaccine | 300 ug | Intramuscular |