drugset / Trial / NCT05638854

A Study to Evaluate Safety and Pharmacokinetics of ZB002 in Healthy Participants and Participants With Rheumatoid Arthritis

NCT05638854 ↗

Phase 1 Recruiting 72 enrolled Zenas BioPharma (USA), LLC
RandomizedSequentialQuadruple-blindTreatment

Summary

This double-blind, randomized, placebo-controlled study will assess the safety and pharmacokinetics of ZB002 in healthy participants and in participants with rheumatoid arthritis (RA). The study consists of 2 parts. Part A: Single Ascending Dose (SAD), which will include only healthy volunteers. Part B: Multiple Ascending Dose (MAD), will commence after completion of the SAD study and will include RA participants.

Timeline

Start
2022-12-08
Primary completion
2025-07
Completion
2025-07

Drugs

EvaluationDrugModalityDoseRoute
Subject ZB002 Unknown — Subcutaneous

Indications