drugset / Trial / NCT05638984

Low Dose Decitabine in Combination With Tirelizumab Comparison of Tirelizumab in the First-line Treatment of Advanced Esophageal Squamous Cell Carcinoma

NCT05638984

Phase 2 Unknown 60 enrolled Fudan University
RandomizedParallel-groupOpen-labelTreatment

Summary

To evaluate the efficacy and safety of low-dose decitabine combined with tirelizumab in the treatment of patients with advanced esophageal squamous cell carcinoma who did not progress in first-line immunotherapy combined with chemotherapy.

Timeline

Start
2023-01-01
Primary completion
2023-12-31
Completion
2024-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Decitabine Small molecule 10 mg Intravenous
Subject Tirelizumab Monoclonal antibody 200 mg Intravenous

Indications

No indication recorded.