drugset / Trial / NCT05646459

Effect of Local Cannabidiol on Clinical and Inflammatory Outcomes in Periodontal Maintenance Patients.

NCT05646459

Phase 1 Withdrawn University of Nebraska
RandomizedParallel-groupTriple-blindTreatment

Summary

This study will determine if cannabidiol (CBD) has any effect on local inflammation in periodontal maintenance patients. Many successful therapies exist for the active, untreated periodontal patient. Unfortunately, periodontology has not yet discovered a therapy that will predictably treat local inflammation in patients who are at risk for further pocketing, bleeding on probing, bone loss and ultimately, tooth loss. Although CBD has been patented in various forms since the 1940s, its acceptance and availability to patients has only recently expanded. Marketing of CBD to periodontal patients as a means to control inflammation is commonplace online and in CBD-specific shops. In determining if CBD is a successful supplement to conventional periodontal inflammation control therapies, millions of patients could benefit from this treatment.

Timeline

Start
2020-05-14
Primary completion
2020-05-14
Completion
2020-05-14

Drugs

EvaluationDrugModalityDoseRoute
Subject Cannabidiol Other / unclassified Topical