drugset / Trial / NCT05646524

Study of Efficacy and Safety of NM8074 in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy

NCT05646524

Phase 2 Not yet recruiting 12 enrolled NovelMed Therapeutics
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is a Phase II, open-label study designed to evaluate the safety, efficacy, and immunogenicity of NM8074 administered intravenously to adult patients with Paroxysmal Nocturnal Hemoglobinuria (PNH).

Timeline

Start
2026-04
Primary completion
2027-08
Completion
2028-09

Drugs

EvaluationDrugModalityDoseRoute
Subject RUXOPRUBART Monoclonal antibody 20 mg/kg Intravenous