drugset / Trial / NCT05647811

Study of NM8074 in Adult C3 Glomerulopathy Patients

NCT05647811

Phase 1/2 Not yet recruiting 18 enrolled NovelMed Therapeutics
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a Phase Ib, open-label, dose-escalation study designed to evaluate the safety, efficacy, and immunogenicity of NM8074 administered intravenously to patients with C3 Glomerulopathy.

Timeline

Start
2027-05
Primary completion
2029-08
Completion
2030-07

Drugs

EvaluationDrugModalityDoseRoute
Subject RUXOPRUBART Monoclonal antibody 5 mg/kg Intravenous
Subject RUXOPRUBART Monoclonal antibody 10 mg/kg Intravenous
Subject RUXOPRUBART Monoclonal antibody 20 mg/kg Intravenous