drugset / Trial / NCT05648318

Comparison of Oral Lactulose Versus Polyethylene Glycol for Bowel Preparation in Low-risk Patients

NCT05648318

Completed 255 enrolled Zhang Xiaofeng,MD
RandomizedParallel-groupDouble-blindScreening

Summary

Adequate quality of bowel preparation(BP) is essential for colonoscopy. In recently, Kang suggested that for low-risk patients, single dose of 2L PEG is an effective regimen for bowel preparation.However, due to the poor palatability, there still more than 30% patients with 2L regimen experienced nausea or vomiting in our center. Oral lactulose is a treatment for constipation. Several studies have compared the effectiveness between use PEG and lactulose for colonoscopy preparation in average-risk patients. However, the data in low-risk patients is vacant. The objective of current study was to compared the effectiveness of bowel preparation and patient tolerance using lactulose and 2L PEG regimen in low-risk patients.

Timeline

Start
2022-01-08
Primary completion
2022-09-12
Completion
2022-09-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Lactulose Other / unclassified 200 ml Oral
Comparator PEG 4000 Unknown 2000 ml Oral

Indications