drugset / Trial / NCT05649228

Thermosensitivity of a Topical Palmitated Formulation of Capsaicin

NCT05649228

Phase 0 Completed 52 enrolled Carilion Clinic Chorda Pharma, Inc. · collab
RandomizedParallel-groupDouble-blindSupportive care

Summary

This is a study of the effects of capsaicin, the ingredient that makes hot peppers hot. Capsaicin is currently used in topical ointments to provide temporary relief of minor aches and joint pain associated with arthritis, simple backache, strains, and sprains. This is a pilot research study that compares the potential of two different capsaicin creams to cause irritation or burning sensation when a small amount (about the size of a quarter) is applied to each forearm of a participant. The amount of capsaicin used in the creams is the same as those found in over-the-counter capsaicin products. The test creams are experimental.

Timeline

Start
2022-12-13
Primary completion
2024-01-11
Completion
2024-01-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Capsaicin Small molecule 0.1 % Topical
Comparator Capsaicin Palmitate Unknown 0.25 % Topical

Indications

No indication recorded.