drugset / Trial / NCT05650216

Camrelizumab Combined With Neoadjuvant Concurrent Chemoradiotherapy for Resectable Locally Advanced ESCC(NICE-RT)

NCT05650216 ↗

Phase 2 Unknown 50 enrolled Shanghai Chest Hospital
NaSingle-groupOpen-labelTreatment

Summary

NICE-RT study is a "safety run-in" and phase II trial evaluating the safety and efficacy of Camrelizumab combined with Nab-paclitaxel and Carboplatin and Radiotherapy in patients with resectable locally advanced esophageal squamous cell carcinoma.

Timeline

Start
2022-12-25
Primary completion
2023-12-25
Completion
2024-12-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Camrelizumab Monoclonal antibody 200 mg Intravenous
Subject Carboplatin Small molecule 2 unknown —
Subject Nab-paclitaxel Small molecule 80 mg/m2 —