drugset / Trial / NCT05651789
Carvedilol vs. Propranolol in Second Prophylaxis of Variceal Bleeding
Unknown
160 enrolled
West China Hospital
Chengdu Shangjin Nanfu Hospital · collabWest China Tianfu Hospital · collab
RandomizedParallel-groupOpen-labelPrevention
Summary
This randomized controlled trial was conducted to evaluate the efficacy and safety of carvedilol versus propranolol, combined with routine endoscopic treatment, in the secondary prophylaxis of variceal bleeding in patients with cirrhosis.
Timeline
- Start
- 2023-01
- Primary completion
- 2024-12
- Completion
- 2024-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carvedilol | Other / unclassified | 12.5 mg | — |
| Comparator | Propranolol | Small molecule | 160 mg | — |