drugset / Trial / NCT05652751

Effect of EA Combined With NGF on Limb Function in Convalescent Patients With Ischemic Stroke

NCT05652751

RandomizedParallel-groupTriple-blindTreatment

Summary

Most ischemic stroke patients are in recovery phase, often accompanied by motor impairment, but they lack effective treatment. The appearance of nerve growth factor (NGF) promotes the development of neuroprotective therapy, but it has little effect on stroke because of the blood-brain barrier (BBB). Electroacupuncture (EA) has been used for stroke, while there is no significant clinical effect for recovery phrase. Consequently, we will conduct a multicentre, randomised, controlled, assessor-blinded clinical trial to assess the effectiveness and safety of EA combined with NGF treatment on ischemic stroke recovery.

Timeline

Start
2022-03-01
Primary completion
2023-02-01
Completion
2023-06-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator nerve growth factor Cell therapy 20 ug Intramuscular

Indications