drugset / Trial / NCT05653427

A Study of Amivantamab Monotherapy in Participants With Previously Treated Advanced Hepatocellular Carcinoma

NCT05653427 ↗

Phase 2 Terminated 18 enrolled Janssen Research & Development, LLC
NaSequentialOpen-labelTreatment

Summary

The purpose of this study is to characterize the preliminary antitumor activity of amivantamab at the recommended dose in participants with previously systemically treated hepatocellular carcinoma (HCC)

Timeline

Start
2022-12-08
Primary completion
2023-10-10
Completion
2023-10-10

Outcome

Outcome not reported

Stopped (Enrollment): “N\~15 subjects data analysis did not meet statistical consideration of ORR and study primary/secondary objectives were not met. Enrollment was terminated for futility”

Drugs

EvaluationDrugModalityDoseRoute
Subject Amivantamab Monoclonal antibody — Intravenous