drugset / Trial / NCT05653492
Safety, Feasibility, and Tolerability of Sulforaphane in Children with Chronic Kidney Disease
RandomizedParallel-groupOpen-labelTreatment
Summary
This purpose of this study is to investigate potential new therapeutics in pediatric chronic kidney disease (CKD). The specific aims are to identify safe dosing and tolerability of sulforaphane (SFN) supplementation in children with moderate and advanced CKD. Secondary objectives will include preliminary exploration of changes in oxidative and inflammatory biomarkers in response to SFN supplementation in this population.
Timeline
- Start
- 2023-05-15
- Primary completion
- 2025-04-30
- Completion
- 2025-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Sulforaphane | Small molecule | 30 mg | — |
| Comparator | Sulforaphane | Small molecule | 60 mg | — |
| Comparator | Sulforaphane | Small molecule | 90 mg | — |
| Comparator | Sulforaphane | Small molecule | 120 mg | — |