drugset / Trial / NCT05653492

Safety, Feasibility, and Tolerability of Sulforaphane in Children with Chronic Kidney Disease

NCT05653492

Phase 2 Active not recruiting 12 enrolled University of Rochester Renal Research Institute · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

This purpose of this study is to investigate potential new therapeutics in pediatric chronic kidney disease (CKD). The specific aims are to identify safe dosing and tolerability of sulforaphane (SFN) supplementation in children with moderate and advanced CKD. Secondary objectives will include preliminary exploration of changes in oxidative and inflammatory biomarkers in response to SFN supplementation in this population.

Timeline

Start
2023-05-15
Primary completion
2025-04-30
Completion
2025-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Sulforaphane Small molecule 30 mg
Comparator Sulforaphane Small molecule 60 mg
Comparator Sulforaphane Small molecule 90 mg
Comparator Sulforaphane Small molecule 120 mg

Indications