drugset / Trial / NCT05656131

Fluzoparib in Combination With or Without Camrelizumab for Homologous Recombinant Deficiency (HRD) HER2 Negative Advanced Breast Cancer

NCT05656131

Phase 2 Suspended 80 enrolled wang shusen
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is planned to include 80 patients with HRD positive HER2-negative advanced breast cancer to receive fluzoparib alone or fluzoparib combined with camrelizumab to observe and evaluate the efficacy and safety of fluzoparib combined with or without camrelizumab in the treatment of HRD positive HER2-negative advanced breast cancer.

Timeline

Start
2022-11-23
Primary completion
2026-03-30
Completion
2027-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Camrelizumab Monoclonal antibody 200 mg Intravenous
Subject Fluzoparib Small molecule 150 mg