drugset / Trial / NCT05657457
Improving Neurological Outcome for Acute Basilar Artery Occlusion With Sufficient Recanalization After Thrombectomy by Intraarterial Tenecteplase (INSIST-IT)
Phase 3
Terminated
145 enrolled
General Hospital of Shenyang Military Region
Cerebrovascular Disease Collaboration & Innovation Alliance of Liaoning · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
The potential benefit of intraarterial tenecteplase in acute basilar artery occlusion (BAO) patients with successful reperfusion following endovascular treatment (EVT) has not been studied. The current study aimed to explore the efficacy and safety of intraarterial tenecteplase in acute BAO patients with successful reperfusion after EVT.
Timeline
- Start
- 2023-03-21
- Primary completion
- 2025-05-18
- Completion
- 2025-05-18
Outcome
Outcome not reported
Stopped: “The interim analysis showed the potential harm of intra-arterial TNK.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tenecteplase | Protein / enzyme biologic | — | Other |