drugset / Trial / NCT05657470
Rescue Thrombolysis for Medium Vessel Occlusion (RESCUE-TNK)
Phase 2/3
Completed
80 enrolled
General Hospital of Shenyang Military Region
Cerebrovascular Disease Collaboration & Innovation Alliance of Liaoning · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
The best reperfusion strategy for medium-sized vessel occlusion (MeVO) is not well established. Given the proven treatment effect of intra-arterial thrombolysis in patients with large vessel occlusion (LVO), the investigators hypothesized that intra-arterial tenecteplase (TNK) could increase the recanalization rate of MeVO and thus improve clinical outcome. The current study aimed to explore the safety and efficacy of intra-arterial TNK in patients with MeVO.
Timeline
- Start
- 2023-03-21
- Primary completion
- 2025-06-16
- Completion
- 2025-06-16
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tenecteplase | Protein / enzyme biologic | — | Other |