drugset / Trial / NCT05659810

The Effect of Gabapentin on Spinal Anesthesia Duration

NCT05659810

Phase 0 Completed 50 enrolled Ain Shams University
RandomizedParallel-groupDouble-blindTreatment

Summary

This prospective parallel group double blinded randomized study will be conducted over 60 adult participants between 20 and 60 years ASA (American Association of Anesthesiologists) I and II. The participants will be randomly allocated in 2 groups. Group A will receive 900 mg of gabapentin before surgery in 2 divided doses; 300 mg 10 hours prior to surgery and 600 mg 2 hours before surgery, while group B will receive 2 placebo tablets at the same time. The participants will receive spinal anesthesia in the form of 3ml of hyperbaric bupivacaine 0.5%. Hemodynamics will be recorded every 15 minutes till the end of surgery. Sensory, and motor block progression, and regression will be recorded also.

Timeline

Start
2022-12-26
Primary completion
2023-03-28
Completion
2023-04-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Gabapentin Small molecule 300 mg Oral

Indications

No indication recorded.