A Study to Assess the Safety of TPM502 in Adults With Celiac Disease

Summary

The goal of this clinical trial is to learn about the safety and the pharmacodynamic (PD) effects of TPM502 in adults with celiac disease. The main questions it aims to answer are: * if TPM502 is safe and well tolerated * if TPM502 can induce modifications in parameters indicating that it may induce tolerance to gluten Participants will: * undergo 1-day gluten challenge during screening and after administration of TPM502 or placebo. * receive 2 infusions of TPM502 or placebo, 2 weeks apart

Timeline

Start

2022-12-12

Primary completion

2024-07-04

Completion

2024-08-08

Drugs

Indications