drugset / Trial / NCT05660538

Evaluation of Efficacy and Safety of VX-548 for Painful Diabetic Peripheral Neuropathy (DPN)

NCT05660538

Phase 2 Completed 194 enrolled Vertex Pharmaceuticals Incorporated
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to evaluate the efficacy and safety of VX-548 doses in treating Painful DPN.

Timeline

Start
2022-12-20
Primary completion
2023-10-12
Completion
2023-10-25

Drugs

EvaluationDrugModalityDoseRoute
Comparator Pregabalin Small molecule 100 mg Oral
Subject Suzetrigine Small molecule 23 mg Oral
Subject Suzetrigine Small molecule 46 mg Oral
Subject Suzetrigine Small molecule 69 mg Oral