drugset / Trial / NCT05663736

Effect of Gemigliptin Versus Glimepiride on Cardiac Diastolic Function in Patients With Type 2 Diabetes

NCT05663736

Phase 4 Unknown 80 enrolled Seoul National University Bundang Hospital
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Among DPP-4 inhibitors, gemigliptin is a relatively recently developed drug, and many clinical studies have shown results that are equivalent to or superior to existing DPP-4 inhibitors such as sitagliptin. However, studies on the safety of gemigliptin in cardiovascular disease have not been conducted, and studies on its effect on cardiac function are lacking. Considering the increase in hospitalizations due to heart failure found in some DPP-4 inhibitor studies, investigation of directly effect of gemigliptin on heart function would be clinically important.

Timeline

Start
2020-01-01
Primary completion
2023-10-31
Completion
2023-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemigliptin Small molecule
Comparator Glimepiride Small molecule

Indications

No indication recorded.