drugset / Trial / NCT05666687
An Open-label, Adaptive Design, Positron Emission Tomography Study in Healthy Male Participants to Characterize Receptor Occupancy by MIJ821 in the Brain
Non-randomizedSequentialOpen-labelBasic science
Summary
The purpose of this study is to confirm binding of MIJ821 to the NR2B-containing NMDA receptors in the human brain and assess the PC-RO relationship over time using positron emission tomography (PET).
Timeline
- Start
- 2023-01-11
- Primary completion
- 2023-11-07
- Completion
- 2023-11-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Onfasprodil | Small molecule | — | Intravenous |