drugset / Trial / NCT05667493

An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

NCT05667493 ↗

Phase 3 Enrolling by invitation 1400 enrolled Ionis Pharmaceuticals, Inc. AstraZeneca · collab
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety and tolerability of extended dosing with eplontersen in participants with ATTR-CM.

Timeline

Start
2022-11-30
Primary completion
2029-08
Completion
2029-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Eplontersen Antisense oligonucleotide — Subcutaneous

Indications