drugset / Trial / NCT05667688
Pharmacokinetics and Pharmacodynamics Study of LBS-008 in Healthy Volunteers Aged 50-85
Non-randomizedParallel-groupOpen-labelBasic science
Summary
This is a Phase 1b, parallel single-dose study to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of Tinlarebant when administered as an oral dose to elderly healthy volunteers. This study will evaluate 2 dose levels in 2 cohorts comprising up to a total of 16 participants (8 per cohort). Dose levels will be evaluated in parallel.
Timeline
- Start
- 2022-11-28
- Primary completion
- 2023-01-04
- Completion
- 2023-01-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Tinlarebant | Small molecule | 5 mg | Oral |
| Comparator | Tinlarebant | Small molecule | 10 mg | Oral |