drugset / Trial / NCT05668936
A Thorough QTC Study to Assess the Effect of Cotadutide on Cardiac Repolarization in Healthy Participants
RandomizedParallel-groupDouble-blindTreatment
Summary
This study will investigate the effect of multiple doses of cotadutide on the cardiac activity (QTc interval) of healthy participants.
Timeline
- Start
- 2023-01-03
- Primary completion
- 2023-03-10
- Completion
- 2023-03-10
Outcome
Outcome not reported
Stopped (Business): “Discontinuing the development of cotadutide, a daily injectable GLP-1/glucagon co-agonist, is based on strategic pipeline considerations. The premature closure is not due to any newly observed safety signals or a change in the risk/benefit profile.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cotadutide | Peptide | — | Subcutaneous |
| Subject | Moxifloxacin | Small molecule | — | Oral |